Anticarcinogenic and antioxidant activities of leaves and flowers hydroalcoholic extracts of Nerium oleander L.: PCA analysis and phytochemical content by FTIR spectroscopy
Copyright © 2023 Siham Ayouaz, Izabela Koss-Mikołajczyk, Nawel Adjeroud- Abdellatif, Agnieszka Bartoszek, Radia Arab, Khokha Mouhoubi, Dimas Rahadian Aji Muhammad, Dwi Larasatie Nur , Khodir Madani
This work is licensed under a Creative Commons Attribution 4.0 International License.
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Aims: The aim of this work is the evaluation the anticarcinogenic effect on HT29 cancer cells lines and antioxidant effect of three extracts from different morphological parts (leaves (LE), pink flowers (PFE) and white flowers (WFE)) of Nerium oleander lin. Methods: This research provides the anticarcinogenic activity of extracts from N. oleander white flowers. Principal Component Analysis (PCA) was applied to estimate the relationship between antioxidant and anticarcinogenic activities, and to further understand the similarities and differences between the extracts. Results: All of the extracts exhibited different antioxidant (ABTS, DPPH and FC) and anticarcinogenic activities. FTIR analysis designed the existence of various functional groups in extracts confirming the presence of alcohol, alkanes, amino, aromatic compound and primary alcohol. The PCA results show that the WFE extract exhibits a greater antioxidant activity with a potent potential for inhibiting the cell growth of colorectal cancer HT29 than the two other extracts (LE and PFE). Conclusions: Nerium oleander may therefore be an excellent source of natural antioxidant and anticancer agents, as well as a possible pharmaceutical supplement.
Keywords
How to Cite
Similar Articles
- Enhancing food and nutritional security through Gender-Disaggregated Analysis: A case study of Lake Victoria Shore, Tanzania
- Determination of phthalate esters contents in different types of cheese produced and consumed in Saudi Arabia
- Regulation of food supplements in Algeria: Current situation, issues, and perspectives.
- A UV-Visible spectrophotometric approach to quantify caffeine and carbohydrates in Dhaka's chocolate and candy selection, Bangladesh
- Exploring the interplay between social media addiction, mindful eating, intuitive eating, orthorexia nervosa, and mental health in young adults
- Relationship between dietary habits and cardiovascular disease risk factors among commercial drivers in northeast Nigeria
- Relationship between cultural food taboos and maternal and child nutrition: A systematic literature review
- Influence of Grain Size on the Agglomeration and Quality of Fine Couscous Derived from Decorticated White Sorghum Bicolor L.
- Cyclodextrins for UV Protection in Food, Beverages, and Agricultural Products: A Comprehensive Review
- Association between dietary diversity and nutritional status of children aged 6-59 months in the Tamale Metropolis
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Impact of carob (Ceratonia Ciliqua L) pulp flour supplementation on probiotic viability, milk fermentation and antioxidant capacity during yogurt storage
- Ziziphus lotus (L.) Lam. plant treatment by ultrasounds and microwaves to improve antioxidants yield and quality: An overview
- Development and characterization of sauces formulations based on tomato and garlic powders
- Impact of incorporating sesame oil (Sesamum indicum L.) in an Algerian frying oil and margarine formulation
- Microwave-assisted extraction optimization and conventional extraction of phenolic compounds from coriander leaves: UHPLC characterization and antioxidant activity
- Study of the relationship between nutrition, physical activity and overweight/obesity in children in a school context: Study of the relationship between nutrition, physical activity
- Ultrasound as pre-treatment for microwave drying of Myrtus communis fruits: Influence on phenolic compounds and antioxidant activity
- Physicochemical characterization and antioxidant capacity of the extracted oil from date pits and its effect on storage stability of margarine
- Advantages and Drawbacks of Plant-Based Beverages as Alternatives to Animal Milk: A Multidimensional Review
- Modeling of nitrate leaching kinetics during spinach leaf midribs blanching
NAJFNR is licensed under 